SML1366

CVT-10216

≥98% (HPLC)

• Synonym(s): 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]-benzoic acid, 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic acid, CVT 10216, GS 455534
• Empirical Formula (Hill Notation): C₂₄H₁₉NO₇S
• CAS Number: 1005334-57-5
• Molecular Weight: 465.48
• MDL number: MFCD18072197
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825820
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(O)C1=CC(COC2=CC=C3C(OC=C(C4=CC=C(NS(C)(=O)=O)C=C4)C3=O)=C2)=CC=C1
• InChI: 1S/C24H19NO7S/c1-33(29,30)25-18-7-5-16(6-8-18)21-14-32-22-12-19(9-10-20(22)23(21)26)31-13-15-3-2-4-17(11-15)24(27)28/h2-12,14,25H,13H2,1H3,(H,27,28)
• InChI key: YYOOFJZTRCPVFD-UHFFFAOYSA-N

Description

General description

CVT-10216 is a 5-HT2c agonist.

Biochem/physiol Actions

CVT-10216 is a selective reversible inhibitor of aldehyde dehydrogenase-2 (ALDH-2), thereby inhibiting dopamine synthesis. CVT-10216 is active in suppressing alcohol and cocaine use, and anxiety.

CVT-10216 is a selective reversible inhibitor of aldehyde dehydrogenase-2.

CVT-10216 possesses unequivocal anxiolytic properties. It will not affect the suppression of locomotor activity by mCPP (m-chlorophenylpiperazine).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable