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About This Item
Empirical Formula (Hill Notation):
C84H140N14O18S
CAS Number:
Molecular Weight:
1666.16
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
Assay
≥80% (HPLC)
form
powder
color
white to off-white
solubility
H2O: soluble
storage temp.
−20°C
Biochem/physiol Actions
FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB.
FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein LP44 of Mycoplasma salivarium. FSL-1 showed higher stimulatory activity than MALP-2 in its ability to induce TNF-α production in macrophages and NF-κB in TLR2/TLR6 transfected HEK293 cells.
FSL-1 is a bacterial-derived toll-like receptor 2/6 agonist. It is capable of increasing resistance to herpes simplex virus type 2 (HSV-2) infection.
Reconstitution
Reconstitute in endotoxin-free water.
Other Notes
Air sensitive
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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