SML2486

Peramivir trihydrate

≥98% (HPLC)

• Synonym(s): (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid trihydrate
• Empirical Formula (Hill Notation): C₁₅H₂₈N₄O₄ · 3H₂O
• CAS Number: 1041434-82-5
• Molecular Weight: 382.45
• UNSPSC Code: 51111800
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -125 to -145°, c = 0.1 in H₂O
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N([C@H]1[C@@H]([C@@H]([C@H](C1)C(=O)O)O)[C@@H](NC(=O)C)C(CC)CC)C(=N)N.O.O.O
• InChI: 1S/C15H28N4O4.3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0.../s1
• InChI key: RFUCJKFZFXNIGB-ZBBHRWOZSA-N

Description

Biochem/physiol Actions

Influenza viral neuraminidase inhibitor

Peramivir exhibits antiviral activity against type A and B influenza virus including pandemic influenza A/H1N1 virus. It also exhibits its antiviral effects on avian influenza viruses like H5N1 and H9N2 strains.

Peramivir is an Influenza viral neuraminidase inhibitor.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable