V9879
[Arg8]-Vasopressin acetate salt
≥95% (HPLC)
Synonym(s):
β-Hypophamine, AVP, Antidiuretic hormone, Arginine vasopressin
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About This Item
Empirical Formula (Hill Notation):
C46H65N15O12S2 · xC2H4O2
CAS Number:
Molecular Weight:
1084.23 (free base basis)
EC Number:
MDL number:
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.32
Biological source:
synthetic (organic)
Form:
powder
biological source
synthetic (organic)
Quality Level
sterility
non-sterile
Assay
≥95% (HPLC)
form
powder
solubility
water: 20.0-20.8 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
−20°C
SMILES string
CC(O)=O.N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O
Related Categories
Amino Acid Sequence
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]
General description
Arginine vasopressin is a nonapeptide. It is produced by anterior hypothalamus nerve cells.
Application
[Arg8]-Vasopressin acetate salt has been:
- used as a vasopressin receptor agonist to test vasopressin receptors
- used to evoke peripheral V1a receptor-mediated vasoconstriction
- as a supplement in Ham′s F12/Dulbecco′s modified Eagle′s medium for proximal tubule and glomerular explant cell culture
Biochem/physiol Actions
Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg8-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).
Endogenous antidiuretic hormone in most mammalian species; neurotransmitter in the central nervous system implicated in a variety of physiological processes including diuresis, vasoregulation, and memory.
Preparation Note
[Arg8]-Vasopressin acetate salt dissolves water at 20 mg/ml to yield a clear colorless to faint yellow solution.
Other Notes
Lyophilized from 0.5% acetic acid
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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