253421

3-(2-Iodoacetamido)-PROXYL

free radical

• Synonym(s): 3-(2-Iodoacetamido)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical
• Empirical Formula (Hill Notation): C₁₀H₁₈IN₂O₂
• CAS Number: 27048-01-7
• Molecular Weight: 325.17
• MDL number: MFCD00010161
• UNSPSC Code: 12352101
• PubChem Substance ID: 24855311
• NACRES: NA.22

Properties

• form: solid
• mp: 162-164 °C (lit.)
• functional group: amide; iodo
• storage temp.: 2-8°C
• SMILES string: CC1(C)CC(NC(=O)CI)C(C)(C)N1[O]
• InChI: 1S/C10H18IN2O2/c1-9(2)5-7(12-8(14)6-11)10(3,4)13(9)15/h7H,5-6H2,1-4H3,(H,12,14)
• InChI key: OQIGMSGDHDTSFA-UHFFFAOYSA-N

Description

General description

3-(2-Iodoacetamido)-PROXYL is a free radical used as a spin probe in spin labeling techniques. This technique is helpful in investigating the dynamic aspects of molecular interactions of substances, proteins, lipids, and cell membranes.

Application

Sulfhydryl group specific spin label. Applications include study of ozone-treated human and bovine erythrocyte membrane proteins and the orientation of myosin subfragment on muscle fibers. DNA fragments containing phosphorothioate diesters can be labeled by spin labels.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves