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A3669

Supelco

Acebutolol hydrochloride

analytical standard

Synonym(s):

N-(3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide

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About This Item

Empirical Formula (Hill Notation):
C18H28N2O4 · HCl
CAS Number:
34381-68-5
Molecular Weight:
372.89
EC Number:
251-980-3
MDL number:
MFCD00078860
UNSPSC Code:
41116107
PubChem Substance ID:
329770842
NACRES:
NA.24
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grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl.CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(C)=O

InChI

1S/C18H28N2O4.ClH/c1-5-6-18(23)20-14-7-8-17(16(9-14)13(4)21)24-11-15(22)10-19-12(2)3;/h7-9,12,15,19,22H,5-6,10-11H2,1-4H3,(H,20,23);1H

InChI key

KTUFKADDDORSSI-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153)

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1 of 4

This Item
PHR19071000601A0040000
Acebutolol hydrochloride analytical standard

A3669

Acebutolol hydrochloride

Acebutolol hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

PHR1907

Acebutolol hydrochloride

Acebutolol hydrochloride United States Pharmacopeia (USP) Reference Standard

1000601

Acebutolol hydrochloride

Acebutolol hydrochloride European Pharmacopoeia (EP) Reference Standard

A0040000

Acebutolol hydrochloride

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

format

neat

format

-

format

neat

format

neat

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

-

storage temp.

2-8°C

Gene Information

human ... ADRB1(153)

Gene Information

human ... ADRB1(153)

Gene Information

human ... ADRB1(153)

Gene Information

human ... ADRB1(153)

General description

Acebutolol hydrochloride is a β-adrenergic receptor blocker.[1][2] It is used in the treatment of hypertension, cardiac arrhythmias and angina pectoris.[2]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    056K1622V
    056K1622

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    2013 Nurse's Drug Handbook (2012)
    The effect of acebutolol on the cerebral circulation of man.
    Hares P, et al.
    British Journal of Clinical Pharmacology, 4(3), 373-375 (1977)
    Pratap Neelakantan et al.
    Blood, 121(14), 2739-2742 (2013-02-06)
    Several groups have shown that that the BCR-ABL1 transcript level measured at 3 or 6 months after starting treatment with tyrosine kinase inhibitors strongly predicts clinical outcomes for patients with chronic myeloid leukemia. In this work, we asked whether the
    Marco Tisè et al.
    International journal of legal medicine, 125(3), 411-416 (2011-01-12)
    The main importance in age estimation lies in the assessment of criminal liability and protection of unaccompanied minor immigrants, when their age is unknown. Under Italian law, persons are not criminally responsible before they reach the age of 14. The
    Catherine Blanchet et al.
    International journal of pediatric otorhinolaryngology, 74(8), 959-961 (2010-06-19)
    The successful management of subglottic hemangioma with propranolol has been reported. We report three cases of subglottic hemangioma treated with the cardioselective beta-blocker acebutolol, 8 mg/kg/day. Treatment was efficient in two cases while an open procedure was necessary in the
    View All Related Papers

    Chromatograms

    application for HPLC

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