59464

Trisodium 2-methylcitrate, racemic mixture of diastereomers

≥85% (mixture of diastereomers, NMR)

• Synonym(s): Trisodium 3-carboxy-3-hydroxy-2-methyl-pentanedioate
• Empirical Formula (Hill Notation): C₇H₇Na₃O₇
• CAS Number: 117041-96-0
• Molecular Weight: 272.10
• MDL number: MFCD16875437
• UNSPSC Code: 12352107
• PubChem Substance ID: 329758670
• NACRES: NA.25

Properties

• Quality Level: 100
• Assay: ≥85% (mixture of diastereomers, NMR)
• form: solid
• impurities: ≤5% water
• SMILES string: [Na+].[Na+].[Na+].CC(C([O-])=O)C(O)(CC([O-])=O)C([O-])=O
• InChI: 1S/C7H10O7.3Na/c1-3(5(10)11)7(14,6(12)13)2-4(8)9;;;/h3,14H,2H2,1H3,(H,8,9)(H,10,11)(H,12,13);;;/q;3*+1/p-3
• InChI key: HPLKAWNRQOHUKD-UHFFFAOYSA-K

Description

Application

2-Methylcitrate is a component of the 2-methylcitric acid (2-MCA) cycle that utilizes propionate as a source of carbon and energy in bacteria. Trisodium 2-methylcitrate may be used to study this pathway

Biochem/physiol Actions

MCA is a diagnostic marker metabolite which cumulates in body fluids of patients suffering from the following inherited metabolic diseases: propionic acidemia (PA), methylmalonic aciduris (MMA), holocarboxylase synthetase deficiency (HCSD). There MCA occurs as a mixture of (2S,3S)- and (2R,3S)-stereoisomers.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable