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About This Item
Linear Formula:
CH3SO3CH2CH3
CAS Number:
Molecular Weight:
124.16
Beilstein:
773969
EC Number:
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.25
form
liquid
Quality Level
refractive index
n20/D 1.418 (lit.)
bp
85-86 °C/10 mmHg (lit.)
density
1.206 g/mL at 20 °C
SMILES string
CCOS(C)(=O)=O
InChI
1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3
InChI key
PLUBXMRUUVWRLT-UHFFFAOYSA-N
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Application
Ethyl methanesulfonate had been used for inducing mutation in mouse embryonic fibroblasts, yeast human embryonic kidney cell lines and human lymphocytes.
Biochem/physiol Actions
Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
212.0 °F
Flash Point(C)
100 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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