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PRS4887

Sigma-Aldrich

Anti-IL-17 (ab2) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-CTLA8, Anti-Interleukin 17A

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5 MG
CA$323.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CA$323.00


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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

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This Item
SAB3701439SAB5700648PRS3797
antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

species reactivity

human, mouse

species reactivity

human

species reactivity

mouse, human, rat

species reactivity

human, mouse

technique(s)

immunofluorescence: suitable, indirect ELISA: suitable, immunohistochemistry: suitable, western blot: suitable

technique(s)

flow cytometry: suitable, western blot: suitable

technique(s)

western blot: 1:500-1:2000

technique(s)

immunocytochemistry: suitable, indirect ELISA: suitable, western blot: suitable

General description

IL-17A (interleukin 17A) is a proinflammatory cytokine of Th17 (helper T cells). It is located on chromosome 6p12.

Immunogen

a 19 amino acid peptide from near the center of human IL-17A.

Biochem/physiol Actions

IL-17A (interleukin 17A) plays a major role in the pathogenesis of autoimmune diseases like multiple sclerosis and rheumatoid arthritis. It also plays a pathogenic role in allergic rhinitis (AR). It helps in the formation of several chemokines and cytokines in airway epithelial cells.

Linkage

The action of this antibody can be blocked using blocking peptide SBP4887.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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