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SAB1401367

Sigma-Aldrich

Monoclonal Anti-SNAI1 antibody produced in mouse

clone 1A5, purified immunoglobulin, buffered aqueous solution

Synonym(s):

SLUGH2, SNA, SNAH, dJ710H13.1

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6 EA
MYR 336.40

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

MYR 336.40

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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1A5, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

capture ELISA: suitable
immunoprecipitation (IP): suitable
western blot: 1-5 μg/mL

isotype

IgG1κ

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513040

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assay

98%

assay

99%

assay

98%

assay

98%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

61-62.5 °C (lit.)

mp

213-215 °C (lit.)

mp

132-135 °C (lit.)

mp

114-117 °C (lit.)

form

crystals

form

powder

form

-

form

-

General description

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. (provided by RefSeq)

Immunogen

SNAI1 (NP_005976.2, 121 a.a. ~ 230 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRSHTLPCVCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTH

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Certificates of Analysis (COA)

    Lot/Batch Number
    09160-1A5

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    Stefan Hirschberg et al.
    eLife, 6 (2017-10-14)
    The locus coeruleus (LC) projects throughout the brain and spinal cord and is the major source of central noradrenaline. It remains unclear whether the LC acts functionally as a single global effector or as discrete modules. Specifically, while spinal-projections from
    Wenjie Ren et al.
    Nature neuroscience, 19(2), 220-222 (2015-12-23)
    We examined adaptations in nucleus accumbens (NAc) neurons in mouse and rat peripheral nerve injury models of neuropathic pain. Injury selectively increased excitability of NAc shell indirect pathway spiny projection neurons (iSPNs) and altered their synaptic connectivity. Moreover, injury-induced tactile

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