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IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

동의어:
IMPD2, IMPDH-II
:
UniProtKB ID:
Clone ID:
  • Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
  • Mouse(23918) inosine 5'-phosphate dehydrogenase 2
  • Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
  • Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2

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Antibodies

Product Number
설명
종별 반응성
응용분야
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunoprecipitation (IP)

western blot
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-IMPDH2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
응용분야
western blot
Anti-IMPDH2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot

Small Molecule - Inhibitor

Product Number
설명
β-Nicotinamide adenine dinucleotide, reduced dipotassium salt, ,
human
Mycophenolic acid, analytical standard,
human
Thioguanine, United States Pharmacopeia (USP) Reference Standard,
human
Mycophenolate mofetil for peak identification, European Pharmacopoeia (EP) Reference Standard,
human
Ribavirin, antiviral,
human

Proteins

Product Number
설명
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
human

esiRNA

Product Number
설명
MISSION® esiRNA, targeting human IMPDH2,
human
MISSION® esiRNA, targeting mouse Impdh2,
mouse