230766

(Trimethylsilyl)isothiocyanate

99%

• 동의어(들): Isothiocyanatotrimethylsilane
• Linear Formula: (CH₃)₃SiNCS
• CAS Number: 2290-65-5
• Molecular Weight: 131.27
• Beilstein: 1745262
• EC Number: 218-929-7
• MDL number: MFCD00004797
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24853836
• NACRES: NA.22

속성

• vapor density: >1 (vs air)
• 분석: 99%
• 양식: liquid
• refractive index: n20/D 1.482 (lit.)
• bp: 143 °C (lit.)
• mp: −32.8 °C (lit.)
• density: 0.931 g/mL at 25 °C (lit.)
• 저장 온도: 2-8°C
• SMILES string: C[Si](C)(C)N=C=S
• InChI: 1S/C4H9NSSi/c1-7(2,3)5-4-6/h1-3H3
• InChI key: XLTUPERVRFLGLJ-UHFFFAOYSA-N

설명

일반 설명

Trimethylsilyl isothiocyanate (TMS-ITC) reacts with fullerene-mixed peroxide C₆₀(O)(OOtBu)₄ to yield isothiocyanate derivative C₆₀(NCS)(OH)(OOtBu)₄. TMS-ITC undergoes condensation with ethyl 2-benzylamino-5-methyl-3-phenylcyclopent-1-enecarboxylate to yield 1-benzyl-5-methyl-7-phenyl-2-thioxo-1,2,3,5,6,7-hexahydrocyclopentapyrimidin-4-one. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.

애플리케이션

Trimethylsilyl isothiocyanate was used as derivatizing reagent during the synthesis of amino acid thiohydantoins.

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H226,H301 + H311 + H331,H315,H319,H334,H335
• 예방조치 성명서: P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 84.2 °F - closed cup
• Flash Point (°C): 29 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter