479306

cis-Diamineplatinum(II) dichloride

≥99.9% trace metals basis

• 동의어(들): cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin
• Linear Formula: Pt(NH₃)₂Cl₂
• CAS Number: 15663-27-1
• Molecular Weight: 300.05
• EC Number: 239-733-8
• MDL number: MFCD00011623
• UNSPSC 코드: 12161600
• PubChem Substance ID: 24871609
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥99.9% trace metals basis
• 반응 적합성: core: platinum; reagent type: catalyst
• mp: 270 °C (lit.)
• 항생제 활성 스펙트럼: neoplastics
• 동작 모드: DNA synthesis | interferes
• SMILES string: N.N.Cl[Pt]Cl
• InChI: 1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
• InChI key: LXZZYRPGZAFOLE-UHFFFAOYSA-L

설명

애플리케이션

cis-Diamineplatinum(II) dichloride can be used as a model drug to test the efficiency of various drug carriers in drug delivery.

Highly active chemotherapeutic agent for use in preventing the advancement of testicular cancer.

생화학적/생리학적 작용

Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H300,H315,H317,H319,H334,H335,H350
• 예방조치 성명서: P202 - P261 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges