597988

Cyclopropylboronic acid

• 동의어(들): Cyclopropaneboronic acid
• 실험식(Hill 표기법): C₃H₇BO₂
• CAS Number: 411235-57-9
• Molecular Weight: 85.90
• MDL number: MFCD04038750
• UNSPSC 코드: 12352103
• PubChem Substance ID: 24881728
• NACRES: NA.22

속성

• 양식: solid
• Quality Level: 100
• mp: 90-95 °C (lit.)
• 저장 온도: −20°C
• SMILES string: OB(O)C1CC1
• InChI: 1S/C3H7BO2/c5-4(6)3-1-2-3/h3,5-6H,1-2H2
• InChI key: WLVKDFJTYKELLQ-UHFFFAOYSA-N

설명

애플리케이션

Boronic acid component in a study of carbon-hydrogen bond alkylation in the presence of Pd(II), Ag(I) and benzoquinone.

Cu-mediated N-cyclopropanation

Reagent used for

• Microwave-assisted copper(II)-catalyzed N-cyclopropylation
• Nickel- and copper-catalyzed Suzuki-Miyaura coupling reaction of arenes
• Palladacycle-catalyzed Suzuki-cross coupling of aryl halides with cyclopropylboronic acid
• Palladium(0)-catalyzed cyclopropane C-H bond functionalization
• Palladium-catalyzed decarboxylative coupling
• Palladium-catalyzed ligand-directed oxidative functionalization of cyclopropanes
• Palladium-catalyzed Suzuki coupling reaction

Reagent used in Preparation of

• Diaryl ketones by arylation of arylboronic acids with aromatic aldehydes catalyzed by Cu(OTf)₂ and Xantphos
• Aminothiazolylpyrrolidine-based tartrate diamides as TACE inhibitors to treat inflammatory disorders and cancer

기타 정보

Contains varying amounts of anhydride

May contain 3-5% cyclopropanol

May contain 5-10% boric acid

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H360FD
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable