760668

Dibenzocyclooctyne-maleimide

for Copper-free Click Chemistry

• 동의어(들): DBCO-maleimide
• 실험식(Hill 표기법): C₂₅H₂₁N₃O₄
• Molecular Weight: 427.45
• MDL number: MFCD22380750
• UNSPSC 코드: 12352111
• PubChem Substance ID: 329766887
• NACRES: NA.22

속성

• Quality Level: 100
• 양식: solid
• 반응 적합성: reaction type: click chemistry; reagent type: cross-linking reagent
• 작용기: maleimide
• 저장 온도: −20°C
• SMILES string: O=C(N1CCC(NCCC(N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4)=O)=O)C=CC1=O
• InChI: 1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)
• InChI key: NHFQNAGPXIVKND-UHFFFAOYSA-N

설명

애플리케이션

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

• Protein-peptide conjugates
• Antibody-enzyme or antibody-drug conjugates
• Protein or peptide-oligonucleotide conjugates
• Surface modification

안전성 정보

• 픽토그램: GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H400
• 예방조치 성명서: P273
• Hazard Classifications: Aquatic Acute 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable