927600

BrBT-alkyne

≥95%

• 동의어(들): 2-Bromo-N-(prop-2-yn-1-yl)benzo[d]thiazole-6-carboxamide
• 실험식(Hill 표기법): C₁₁H₇BrN₂OS
• CAS Number: 2550395-96-3
• Molecular Weight: 295.16
• MDL number: MFCD34622465
• UNSPSC 코드: 12352101
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95%
• 양식: powder
• 저장 온도: −20°C
• SMILES string: BrC1=NC2=CC=C(C(NCC#C)=O)C=C2S1
• InChI: 1S/C11H7BrN2OS/c1-2-5-13-10(15)7-3-4-8-9(6-7)16-11(12)14-8/h1,3-4,6H,5H2,(H,13,15)
• InChI key: MRYSQSUDZPBHGP-UHFFFAOYSA-N

설명

애플리케이션

BrBT-alkyne is a probe that can be used to lable cysteines through nucleophilic aromatic substitution. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitave applications (Zanon et al. 2021). The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis (Zanon et al. 2020). Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow (Weerapana et al. 2010, Backus et al. 2016).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable