933546

NanoFabTx^™ - Natural Folate Lipid Mix

for synthesis of folate functionalized liposomes for targeted delivery

• 동의어(들): Cholesterol, EggPC, Folate-PEG-DSPE, PE-PEG
• UNSPSC 코드: 12352211
• NACRES: NA.21

속성

• Quality Level: 100
• 저장 온도: −20°C

설명

애플리케이션

NanoFabTx^™ Natural Folate Lipid Mix is a ready-to-use nanoformulation lipid mixture for the synthesis of folate-functionalized liposomes. This lipid mix enables users to encapsulate a wide variety of therapeutic drug molecules for targeted drug delivery applications without the need for lengthy trial-and-error optimization.
NanoFabTx^™ Natural Folate Lipid Mix is a lyophilized, curated, lipid mixture containing rationally selected lipids in precise ratios that have been optimized to achieve liposomes of approximately 100nm in diameter. The synthesized folate-functionalized liposomes can be used to selectively target cells which overexpress folate receptors such as HeLa cells and delivery hydrophilic or hydrophobic drugs, including therapeutics that are thermo-sensitive.

특징 및 장점

• A ready-to-use nanoformulation lipid blend for the synthesis of folate-functionalized liposomes without the need for high temepratures
• Step-by-step protocols developed and tested by our formulation scientists
• Flexible synthesis tool to create uniform and reproducible liposomes
• Optimized to make liposomes around 100 nm with low polydispersity
• Optimized lipid blend for folate-functionalized liposomes for therapeutic encapsulation

For microfluidic liposome synthesis of azide-functionalized liposomes, the NanoFabTx^™- Natural Folate Lipid Mix can be used with the the NanoFabTx^™Microfluidic - nano device kit (Cat.No. 911593). The NanoFabTx^™Microfluidic - nano device kit includes the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).

법적 정보

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3