A78403

4-Aminopyridine

98%

• 동의어(들): 4-Pyridinamine, 4-Pyridylamine, 4AP, Fampridine
• 실험식(Hill 표기법): C₅H₆N₂
• CAS Number: 504-24-5
• Molecular Weight: 94.11
• Beilstein: 105782
• EC Number: 207-987-9
• MDL number: MFCD00006439
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24891285
• NACRES: NA.22

속성

• 분석: 98%
• 양식: crystals
• bp: 273 °C (lit.)
• mp: 155-158 °C (lit.)
• solubility: H₂O: 50 mg/mL, clear, colorless
• SMILES string: Nc1ccncc1
• InChI: 1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
• InChI key: NUKYPUAOHBNCPY-UHFFFAOYSA-N
• 유전자 정보: human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522) ; mouse ... Kcna3(16491) ; rat ... Grin2a(24409)

설명

일반 설명

4-aminopyridine is a ligand and an ion channel modulator used as an acetylcholine release enhancing agent.

애플리케이션

4-Aminopyridine (4-AP) can be used as a:

• Catalyst in the regioselective acylation of N-tosylhydrazide.
• Starting material in the synthesis of 4-aminopyridine derivatives for neurological disorder studies.
• Precursor for the synthesis of enantiomerically pure 4-(pyrrolidino)pyridine (PPY) derivatives by cyclocondensation reaction.

안전성 정보

• 픽토그램: GHS06,GHS05,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H300,H311 + H331,H314,H411
• 예방조치 성명서: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): 312.8 °F
• Flash Point (°C): 156 °C
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges