870606P

POVPC

Avanti Research^™ - A Croda Brand 870606P, powder

• 동의어(들): 1-palmitoyl-2-(5′-oxo-valeroyl)-sn-glycero-3-phosphocholine
• 실험식(Hill 표기법): C₂₉H₅₆NO₉P
• CAS Number: 121324-31-0
• Molecular Weight: 593.73
• MDL number: MFCD05863929
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 1 mg (870606P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 870606P
• 지질 유형: phosphoglycerides; phospholipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCC([H])=O)=O)COC(CCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C29H56NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-20-28(32)36-25-27(39-29(33)21-18-19-23-31)26-38-40(34,35)37-24-22-30(2,3)4/h23,27H,5-22,24-26H2,1-4H3/t27-/m1/s1
• InChI key: RKIDALSACBQVTN-HHHXNRCGSA-N

설명

일반 설명

1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) is a derivative of oxidized Low density lipoprotein (oxLDL), a proinflammatory lipid present in atherosclerotic lesions.

애플리케이션

1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) has been used:

• to study its effects on endothelial function and vasodilation
• as a ligand for LRP6 in bone marrow mesenchymal stromal cells (MSCs)
• as a oxidized lipid to study if membrane status at different degrees of lipid peroxidation is involved in oxidative stress tolerance

생화학적/생리학적 작용

1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) affects endothelial function by hindering activity of endothelial nitric oxide synthase and stimulating endothelial cell apoptosis. It is implicated in the development of atherosclerosis and it may be used as a potent therapeutic for atherosclerosis.

포장

5 mL Clear Glass Sealed Ampule (870606P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids