Name: Bilirubin
Brand: MM

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About This Item

실험식(Hill 표기법):

C₃₃H₃₆N₄O₆

CAS Number:

635-65-4

Molecular Weight:

584.66

MDL number:

MFCD00005499

UNSPSC 코드:

12352200

NACRES:

NA.77

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도움 문의

Product Name

Bilirubin, Principal pigment of bile and one of the major end products of hemoglobin decomposition.

Quality Level

100

설명

RTECS - DU3038000
Merck USA index - 14, 1218

양식

solid

제조업체/상표

Calbiochem^®

저장 조건

OK to freeze
protect from light

색상

red-brown

solubility

chloroform: 1 mg/mL
alkaline solution: soluble

배송 상태

ambient

저장 온도

10-30°C

SMILES string

[nH]1c(c(c(c1\C=C4/NC(=O)C(=C/4C)C=C)C)CCC(=O)O)Cc2[nH]c(c(c2CCC(=O)O)C)\C=C3/NC(=O)C(=C/3C=C)C

InChI

1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-

InChI key

BPYKTIZUTYGOLE-IFADSCNNSA-N

일반 설명

Bilirubin is an orange-yellow bile pigment and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. In adults, the upper limit of the normal range of bilirubin is >1mg/dL. Serum levels of bilirubin in healthy newborns are less than 15 mg/dl. This product corresponds to the unconjugated form.

생화학적/생리학적 작용

Bilirubin is reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This pigment aids in coloration in the various forms of jaundice. Bilirubin levels act as biomarkers in liver and blood disorders. Unconjugated form of bilirubin at lower levels serves as a physiological antioxidant. However, increased concentration of bilirubin is toxic and leads to neonatal hyperbilirubinemia in neonates.

재구성

Unstable in basic solutions; reconstitute just prior to use.

기타 정보

Extinction coefficient (454 nm, CHCl₃):59,100-62,300 M^-1cm^-1.
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Target

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)