MABN669

Anti-Dopamine Transporter Antibody, clone mAb16

clone mAB16, from mouse

• 동의어(들): Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: mAB16, monoclonal
• 종 반응성: mouse, rat
• 기술: western blot: suitable
• 동형: IgG1
• NCBI 수납 번호: NP_036826
• UniProt 수납 번호: P23977
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Slc6A3(13162) ; rat ... Slc6A3(24898)

설명

일반 설명

The transmembrane dopamine transporter (DAT) is located on the presynaptic nerve terminal and is responsible for terminating dopaminergic transmission by transporting dopamine from the synaptic cleft into the dopaminergic neuron (reuptake). Dopaminergic pathways have been strongly implicated in reward and addiction, motivation, alcoholism, ADHD and degenerative motor diseases such as Parkinson′s, Huntington′s and Chorea. EMD Millipore’s Anti-Dopamine Transporter antibody has been validated in western blotting for mouse and rat specimens.

특이성

This antibody recognizes the cytoplasmic domain of Dopamine Transporter.

면역원

Epitope: Cytoplasmic domain

Linear peptide corresponding to the cytoplasmic domain of rat Dopamine Transporter.

애플리케이션

Anti-Dopamine Transporter Antibody, clone mAb16 is a highly specific mouse monoclonal antibody & that targets Dopamine Transporter & has been tested in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Western Blotting Analysis: A representative lot from an independent laboratory detected Dopamine Transporter in rat striatal membrane tissue lysate.

품질

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Dopamine Transporter in 10 µg of mouse brain tissue lysate.

표적 설명

~ 68 kDa observed

물리적 형태

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Mouse brain tissue lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable