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LIGHTOX19

Sigma-Aldrich

LightOx19

≥95% (HPLC)

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1 EA
₹15,642.00

About This Item

실험식(Hill 표기법):
C23H23NO2
CAS Number:
Molecular Weight:
345.43
UNSPSC 코드:
12352101
NACRES:
NA.22

₹15,642.00


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분석

≥95% (HPLC)

양식

powder

저장 온도

2-8°C

SMILES string

N1(c2c(cc(cc2)C#Cc3ccc(cc3)C(=O)O)C(C=C1)(C)C)C(C)C

InChI key

HXWVRWZLWIKKOS-UHFFFAOYSA-N

애플리케이션

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

생화학적/생리학적 작용

Strong ligand for retinoic acid receptor proteins

특징 및 장점

LightOx19 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx19 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

기타 정보

Chemical Equivalency 1ea=1mg

법적 정보

LightOx is a trademark of LightOx Ltd.


Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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    문서 라이브러리 방문


    문서

    Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.