Name: Succinic acid
Brand: SIAL

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About This Item

Linear Formula:

HOOCCH₂CH₂COOH

CAS Number:

110-15-6

Molecular Weight:

118.09

Beilstein:

1754069

EC Number:

203-740-4

MDL number:

MFCD00002789

UNSPSC 코드:

12352106

PubChem Substance ID:

24899568

NACRES:

NA.25

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Quality Level

200

제품 라인

BioXtra

분석

≥99.0%

환경친화적 대안 제품 특성

Use of Renewable Feedstocks
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불순물

≤0.01% Insoluble matter

무기 잔류물

≤0.02%

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

H₂O: 0.5 M, clear, colorless

음이온 미량물

chloride (Cl^-): ≤0.001%
sulfate (SO₄^2-): ≤0.003%

양이온 미량물

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH₄⁺: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

환경친화적 대안 카테고리

, Aligned

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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애플리케이션

Succinic acid has been used:

in succinate dehydrogenase mitochondrial assay.
as an internal standard in mass spectroscopy.
as succinate dehydrogenase substrate in oxygraph analysis to measure respiration rates.

생화학적/생리학적 작용

Succinic acid is a byproduct of anaerobic fermentation in microbes. It is a dicarboxylic acid and an intermediate in Kreb′s cycle. Polymorphism in succinate dehydrogenase leads to succinate accumulation. High levels of succinate impairs 2-oxoglutarate epigenetic signalling. Succinate levels may modulate tumor progression. Succinate inhibits histone demethylation and may contribute to epigenetic changes. Succinate is crucial for interleukin-1 β (IL-1β) synthesis during inflammation and immune signalling.