A1520

α-Amylase Inhibitor

≥200 inhibitor U/mg protein (using porcine pancreatic α-amylase), ≥1000 inhibitor U/mg protein (using human salivary α-amylase), lyophilized powder

• MDL number: MFCD00130475
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• Product Name: α-Amylase Inhibitor from Triticum aestivum (wheat seed), Type I, lyophilized powder
• 생물학적 소스: Triticum estivum
• Quality Level: 200
• 유형: Type I
• 양식: lyophilized powder
• 특이 활성도: ≥1000 inhibitor U/mg protein (using human salivary α-amylase); ≥200 inhibitor U/mg protein (using porcine pancreatic α-amylase)
• 구성: Protein, 35-65% biuret
• 저장 온도: −20°C

설명

일반 설명

α-Amylases are endoglycosidases, that are classified into glycosyl hydrolase family 13 (1-3).

애플리케이션

α-Amylase Inhibitor from Triticum aestivum (wheat seed) has been used to determine its effects on salivary gland (SG) amylase activity. It has also been used to inhibit the activity from the extract from Bemisia tabaci.

생화학적/생리학적 작용

α-Amylases can hydrolyze α-(1,4)-D-glycosidic linkages. It participates in the breakdown of starch and glycogen. Inhibiting this enzyme can be used as a strategy to treat dental caries, diabetes, obesity and periodontal diseases.

Competitive inhibitor of human salivary α-amylase. K_I = 2.9 nM, compared to a K_M of 5.9 mM (calculated per mole of α-1,4-linked maltose residues).

단위 정의

One unit will reduce the activity of two units of α-amylase (A0521) by 50% after pre-incubation at 25 °C.

물리적 형태

Lyophilized powder containing buffer salts as sodium phosphate.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)