A6150

α₁-Antitrypsin from human plasma

salt-free, lyophilized powder

• 동의어(들): α₁-Proteinase inhibitor
• CAS Number: 9041-92-3
• EC Number: 232-924-7
• MDL number: MFCD00130469
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• 생물학적 소스: human plasma
• Quality Level: 200
• 양식: salt-free, lyophilized powder
• 농도: ≥60% (biuret)
• 기술: inhibition assay: suitable
• UniProt 수납 번호: P01009; P08246
• 저장 온도: 2-8°C
• 유전자 정보: human ... ELA2(1991), ELANE(1991), SERPINA1(5265)

설명

생화학적/생리학적 작용

≤10 mg will inhibit 1.0 mg of trypsin with activity of 10,000 BAEE units per mg protein. ≤10 mg will inhibit approx. 1.0 mg of ·α-chymotrypsin with activity of 40-50 BTEE units per mg protein.

Serine protease inhibitor; inhibits trypsin, chymotrypsin and pancreatic and granulocytic elastase, and acrosin. Effective concentration equimolar with proteinase.

Serine protease inhibitor; inhibits trypsin, chymotrypsin and pancreatic and granulocytic elastase, and acrosin. Effective concentration equimolar with proteinase.The effects of hereditary α₁-antitrypsin deficiency and certain autoimmune states result from uncontrolled proteolysis in vivo. Direct α₁-antitrypsin replacement therapy has shown promise in animal models of Type 1 diabetes.

주의사항

Aqueous stock solutions containing 0.01% NaN₃ are stable for several months. Solutions can be stored at −80 °C, but should not be refrozen. Unstable below pH 5.5. Inactivated by some non-serine proteinases and by oxidation of active site methionine residue.

제조 메모

Chromatographically prepared and partially purified.

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable