C223

Cirazoline hydrochloride

solid

• 동의어(들): 2-[(2-Cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole hydrochloride
• 실험식(Hill 표기법): C₁₃H₁₆N₂O · HCl
• CAS Number: 40600-13-3
• Molecular Weight: 252.74
• EC Number: 254-995-3
• MDL number: MFCD00274034
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277770
• NACRES: NA.77

속성

• 양식: solid
• Quality Level: 100
• 색상: white
• solubility: H₂O: >35 mg/mL
• SMILES string: Cl[H].C1CN=C(COc2ccccc2C3CC3)N1
• InChI: 1S/C13H16N2O.ClH/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13;/h1-4,10H,5-9H2,(H,14,15);1H
• InChI key: XFRXWLWUUDJHPB-UHFFFAOYSA-N
• 유전자 정보: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

설명

애플리케이션

Cirazoline hydrochloride has been used to activate the α1-noradrenergic receptors and to study the inhibitory effect of neurokinin1 (NK1) antagonists on respiratory activity using the brainstem transverse slice.

생화학적/생리학적 작용

Cirazoline is a selective α1-adrenoceptor agonist and also a non-selective ligand for the imidazoline binding site. Cirazoline dereases spatial working memory performance in aged monkeys.

특징 및 장점

This compound is featured on the α1-Adrenoceptors and Imidazoline Binding Sites pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)