Name: Cefotaxime sodium salt
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₁₆H₁₆N₅NaO₇S₂

CAS Number:

64485-93-4

Molecular Weight:

477.45

Beilstein:

5711411

EC Number:

264-915-9

MDL number:

MFCD00079073

UNSPSC 코드:

10171502

PubChem Substance ID:

24892923

NACRES:

NA.72

기술 서비스

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도움 문의

Product Name

Cefotaxime sodium salt, suitable for plant cell culture, BioReagent, powder or crystals

제품 라인

BioReagent

Quality Level

200

양식

powder or crystals

기술

cell culture | plant: suitable

색상

off-white to pale yellow

solubility

H₂O: 10% ( )

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

응용 분야

agriculture

동작 모드

cell wall synthesis | interferes

저장 온도

2-8°C

SMILES string

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI key

AZZMGZXNTDTSME-JUZDKLSSSA-M

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일반 설명

Chemical structure: ß-lactam

애플리케이션

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.

생화학적/생리학적 작용

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.

Mode of Action: Inhibits bacterial cell wall synthesis.