C7642

Concanavalin A from Canavalia ensiformis (Jack bean)

FITC conjugate, Type IV, lyophilized powder

• 동의어(들): ConA
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: Canavalia ensiformis
• Quality Level: 200
• 결합: FITC conjugate
• 유형: Type IV
• 양식: lyophilized powder
• 구성: Protein, 5-15% biuret
• 라벨링 범위: 3-6 mol FITC per mol protein
• 불순물: Carbohydrate, essentially free
• 저장 온도: −20°C

설명

애플리케이션

For the fluorescent detection of glycoproteins containing α−D-mannose or α−D-glucose

생화학적/생리학적 작용

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

포장

Package size based on protein content

물리적 형태

Lyophilized powder containing phosphate buffer salts and NaCl

분석 메모

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca²⁺ and Mn²⁺ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317
• 예방조치 성명서: P280 - P302 + P352
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves