Name: Cephradine
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₁₆H₁₉N₃O₄S

CAS Number:

38821-53-3

Molecular Weight:

349.40

MDL number:

MFCD00865048

UNSPSC 코드:

51282517

PubChem Substance ID:

24278342

NACRES:

NA.85

기술 서비스

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도움 문의

Quality Level

200

분석

≥90.0% (Cephradine, HPLC)

양식

powder

solubility

ethanol: practically insoluble 96%
hexane: practically insoluble
water: slightly soluble

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

동작 모드

cell wall synthesis | interferes

저장 온도

2-8°C

SMILES string

[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CCC=CC3)C(O)=O

InChI

1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1

InChI key

RDLPVSKMFDYCOR-UEKVPHQBSA-N

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일반 설명

Chemical structure: ß-lactam

애플리케이션

Cefradin was used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.

생화학적/생리학적 작용

Cefradin is a semi-synthetic cephalosporin that inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), such as PBP3, which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. It is effective against Gram-positive and Gram-negative bacteria. Cefradin may also interfere with autolysin inhibitors.