생물학적 소스
synthetic (organic)
Quality Level
분석
≥99% (HPLC)
양식
powder
solubility
water: 50 mg/mL, clear, colorless to very faintly yellow
저장 온도
−20°C
SMILES string
NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2
InChI
1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1
InChI key
CKTSBUTUHBMZGZ-SHYZEUOFSA-N
관련 카테고리
일반 설명
2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides containing cytosine as the nucleobase. It is found in the blood, feces, and urine.
애플리케이션
2′-Deoxycytidine has been used:
- as a substrate for Trypanosoma brucei cytidine deaminase (TbCDA) to measure its activity
- as a standard in the isolation and quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC–MS)
- to study the role of autophagy in response to oncogenes and DNA replication stress
생화학적/생리학적 작용
2′-Deoxycytidine (deoxyC) forms dCTP upon phosphorylation which is used to synthesis DNA via various DNA polymerases or reverse transcriptases. DeoxyC is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. DeoxyC is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK). DeoxyC serves as a potential head and neck cancer marker.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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