Name: 3,4-Dihydroxy-<SC>L-</SC>phenylalanine
Brand: SIGMA

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About This Item

Linear Formula:

(HO)₂C₆H₃CH₂CH(NH₂)CO₂H

CAS Number:

59-92-7

Molecular Weight:

197.19

Beilstein:

2215169

EC Number:

200-445-2

MDL number:

MFCD00002598

UNSPSC 코드:

12352209

eCl@ss:

32160406

PubChem Substance ID:

24277914

NACRES:

NA.32

기술 서비스

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Product Name

3,4-Dihydroxy-L-phenylalanine, ≥98% (TLC)

Quality Level

200

분석

≥98% (TLC)

양식

powder

색상

white to off-white

mp

276-278 °C (lit.)

응용 분야

peptide synthesis

저장 온도

room temp

SMILES string

N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O

InChI

1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

InChI key

WTDRDQBEARUVNC-LURJTMIESA-N

유전자 정보

human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)
mouse ... DRD1(13488), DRD2(13489), DRD3(13490), DRD4(13491), DRD5(13492)
rat ... DRD1(24316), DRD2(24318), DRD3(29238), DRD4(25432), DRD5(25195)

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애플리케이션

3,4-Dihydroxy-L-phenylalanine or L-DOPA has been used to stain melanocytes. It has also been used to study its effects on a Drosophila model of Parkinson′s disease.

생화학적/생리학적 작용

3,4-Dihydroxy-L-phenylalanine or L-DOPA is a natural isomer of the immediate precursor of dopamine that crosses the blood-brain barrier. It is used for the treatment of Parkinson′s disease and is a product of tyrosine hydroxylase.