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About This Item
Linear Formula:
HCHO
CAS Number:
Molecular Weight:
30.03
Beilstein:
1209228
EC Number:
MDL number:
UNSPSC 코드:
12352114
PubChem Substance ID:
NACRES:
NA.31
Grade:
Molecular Biology
Vapor pressure:
52 mmHg ( 37 °C)
Grade
Molecular Biology
Quality Level
vapor density
1.03 (vs air)
vapor pressure
52 mmHg ( 37 °C)
양식
liquid
autoignition temp.
572 °F
포함
10-15% methanol
농도
36.5-38% in H2O
기술
ChIP: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
density
1.09 g/mL at 25 °C (lit.)
적합성
suitable for (use in Formaldehyde-Agarose Gel Electrophoresis of RNA)
응용 분야
general analytical
genomic analysis
저장 온도
15-25°C
SMILES string
[H]C([H])=O
InChI
1S/CH2O/c1-2/h1H2
InChI key
WSFSSNUMVMOOMR-UHFFFAOYSA-N
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일반 설명
Formaldehyde, a colorless, pungent-smelling chemical, finds extensive application in various biological research and laboratory settings. Primarily supplied as a 37% solution (formalin), its diverse uses range from tissue preservation and sterilization to acting as a denaturant in RNA gel electrophoresis. However, it′s crucial to acknowledge its potential health risks and handle it with appropriate precautions.Multifaceted Functions:
- Preservative: Formaldehyde′s ability to inhibit microbial growth makes it an effective preservative in biological samples, preventing decay and ensuring their integrity for further analysis. This property finds application in medical laboratories, museums, and even embalming fluids.
- Fixative: In histology, formaldehyde acts as a fixative, cross-linking proteins and preserving tissue structures for microscopic examination. This allows researchers to visualize anatomical details and cellular components with remarkable clarity.
- Denaturant: In molecular biology techniques like formaldehyde-agarose gel electrophoresis, formaldehyde denatures RNA molecules, preventing them from forming secondary structures and enabling size-based separation. This technique proves invaluable for studying gene expression and RNA integrity.
애플리케이션
Formaldehyde solution has been used for fixing of cells and tissue sections. It has been used in the formaldehyde agarose gel electrophoresis. Formaldehyde is used as a denaturant in formaldehyde-agarose gel electrophoresis of RNA.
특징 및 장점
- Versatile and adaptable for a wide variety of laboratory and research applications
- Suitable for Molecular Biology and Biochemical applications
분석 메모
Tested for use in formaldehyde-agarose gel electrophoresis of RNA.
기타 정보
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신호어
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3
표적 기관
Eyes,Central nervous system, Respiratory system
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point (°F)
133.0 °F - closed cup
Flash Point (°C)
56.11 °C - closed cup
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