Name: Hydrocortisone
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₂₁H₃₀O₅

CAS Number:

50-23-7

Molecular Weight:

362.46

Beilstein:

1354819

EC Number:

200-020-1

MDL number:

MFCD00011654

UNSPSC 코드:

51111800

PubChem Substance ID:

24278466

NACRES:

NA.77

기술 서비스

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도움 문의

생물학적 소스

synthetic (organic)

Quality Level

300

무균

non-sterile

분석

≥98% (HPLC)

양식

powder

mp

211-214 °C (lit.)

solubility

water: 0.28 g/L at 25 °C

응용 분야

cell analysis

배송 상태

ambient

저장 온도

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

유전자 정보

human ... ABCB1(5243), CYP3A4(1576), NR3C1(2908), SERPINA6(866)
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126)
rat ... Ar(24208), Nr3c1(24413)

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생화학적/생리학적 작용

Primary glucocorticoid secreted by the adrenal cortex.

Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na²⁺ retention potency.

특징 및 장점

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.