H6666

Keratinocyte Growth Factor human

HumanKine^®, >95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture

• 동의어(들): FGF-7, KGF
• CAS Number: 148348-15-6
• MDL number: MFCD00212245
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• Product Name: Keratinocyte Growth Factor human, KGF, recombinant, expressed in HEK 293 cells, HumanKine^®, suitable for cell culture
• 생물학적 소스: human
• 재조합: expressed in HEK 293 cells
• 분석: >95% (SDS-PAGE)
• 양식: lyophilized powder
• 효능: 4-20 ng/mL EC₅₀
• 품질: endotoxin tested
• 분자량: dimer 17-30 kDa (glycosylated)
• 포장: pkg of 10 μg
• 기술: cell culture | mammalian: suitable
• 불순물: <1 EU/μg
• UniProt 수납 번호: P21781
• 저장 온도: −20°C
• 유전자 정보: human ... FGF7(2252)

설명

일반 설명

Keratinocyte Growth Factor (KGF) belongs to the fibroblast growth factor 7 (FGF-7) family. It is produced by the mesenchymal cells, γδ T cells, and fibroblasts in several organs. The KGF gene is located on the human chromosome at 15q21.2.

애플리케이션

Keratinocyte Growth Factor (KGF) human has been used as a component of the keratinocyte differentiation medium.

생화학적/생리학적 작용

Keratinocyte Growth Factor (KGF) exerts paracrine effects on mesenchymal cells. It exhibits cryoprotective effects on epithelial cells of the lungs, gastrointestinal tract, and the lungs. KGF participates in the activation of IIIb isoform of the fibroblast growth factor (FGF)-receptor 2 (FGFR2-IIIb) present on keratinocytes. This activation further favors proliferation, migration, and survival of keratinocytes.

물리적 형태

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

제조 메모

HumanKine Keratinocyte Growth Factor (KGF) is expressed as glycosylated 17 and 30 kDa monomers in human HEK 293 cells. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.

분석 메모

The activity was determined by the dose-dependent stimulation of the proliferation of 4MBr-5 cells (monkey epithelial cell line).

법적 정보

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable