I7784

Anti-Interleukin-2 antibody produced in goat

affinity isolated antibody, lyophilized powder

• 동의어(들): Anti-IL-2
• MDL number: MFCD00675261
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: goat
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: lyophilized powder
• 종 반응성: rat, mouse
• 기술: neutralization: suitable; western blot: 0.1-0.2 μg/mL
• UniProt 수납 번호: P04351
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Il2(16183) ; rat ... Il2(116562)

설명

일반 설명

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4⁺ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signalling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signalling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle
Monoclonal Anti-Interleukin-2 recognizes murine Interleukin-2. It does not react with human IL-2, but will react with rabbit IL-2 at a 100x higher IgG concentration.

면역원

purified, E. coli-derived recombinant mouse interleukin-2.

애플리케이션

Anti-interleukin-2 antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml. The antibody is suitable for murine IL-2 neutralization assays.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)