Name: Kanamycin solution from <I>Streptomyces kanamyceticus</I>
Brand: SIGMA

로그인조직 및 계약 가격 보기

About This Item

CAS Number:

25389-94-0

MDL number:

MFCD00070289

UNSPSC 코드:

12352207

PubChem Substance ID:

329817120

NACRES:

NA.76

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

Product Name

Kanamycin solution from Streptomyces kanamyceticus, 50 - 60 mg/mL in 0.9% NaCl, BioReagent, liquid, 0.1 μm filtered, suitable for cell culture

생물학적 소스

Streptomyces kanamyceticus

Quality Level

200

무균

0.1 μm filtered

제품 라인

BioReagent

양식

liquid

농도

50 - 60 mg/mL in 0.9% NaCl

기술

cell culture | mammalian: suitable
cell culture | plant: suitable

불순물

endotoxin, tested

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria
mycobacteria
mycoplasma

동작 모드

protein synthesis | interferes

저장 온도

2-8°C

SMILES string

NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1

InChI key

SBUJHOSQTJFQJX-NOAMYHISSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Kanamycin sulfate is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus. It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 2 mL/L.

애플리케이션

Kanamycin solution from Streptomyces kanamyceticus has been used:

to induce deafness in neonatal rats
as an endothelial growth medium component for culturing human umbilical vein endothelial cells (HUVECs)
as medium component for Mycobacteria Cultures and Top10 E coli cells

생화학적/생리학적 작용

Mode of Action: The product acts by binding to the 70S ribosomal subunit, inhibiting translocation and eliciting miscoding.

Mode of Resistance: Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes.

Antimicrobial spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma.