L9664

Loratadine

≥98% (HPLC), powder

• 동의어(들): 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Loratidine
• 실험식(Hill 표기법): C₂₂H₂₃N₂O₂Cl
• CAS Number: 79794-75-5
• Molecular Weight: 382.88
• MDL number: MFCD00672869
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278525
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white
• solubility: DMSO: soluble 50 mg/mL; H₂O: insoluble
• 주관자: Schering Plough
• 저장 온도: 2-8°C
• SMILES string: CCOC(=O)N1CC\C(CC1)=C2/c3ccc(Cl)cc3CCc4cccnc24
• InChI: 1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
• InChI key: JCCNYMKQOSZNPW-UHFFFAOYSA-N
• 유전자 정보: human ... CYP3A4(1576), HRH1(3269), KCNH1(3756), KCNH2(3757), PTAFR(5724) ; rat ... Hrh1(24448)

설명

생화학적/생리학적 작용

Loratadine is a non-sedating histamine H1-receptor antagonist. Shown to inhibit the two-pore domain potassium channel K2P18.1 (also called TRESK or KCNK18).

Non-sedating histamine H₁-receptor antagonist.

특징 및 장점

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)