Name: Mometasone furoate
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₂₇H₃₀Cl₂O₆

CAS Number:

83919-23-7

Molecular Weight:

521.43

MDL number:

MFCD00866003

UNSPSC 코드:

51111800

PubChem Substance ID:

329817988

NACRES:

NA.77

기술 서비스

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도움 문의

Quality Level

100

분석

≥98% (HPLC)

양식

powder

광학 활성

[α]/D +50 to +60°, c = 0.5 in methanol

색상

white to off-white

solubility

DMSO: ≥20 mg/mL

주관자

Schering Plough

저장 온도

2-8°C

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c5ccco5)C(=O)CCl

InChI

1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1

InChI key

WOFMFGQZHJDGCX-ZULDAHANSA-N

유전자 정보

human ... NR3C1(2908)

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애플리케이션

Mometasone furoate has been used to study its effect on Leishmania major amastigotes.

생화학적/생리학적 작용

Mometasone furoate is a 17-heterocyclic intranasal corticosteroid. It is effectively used as a first-line daily intranasal therapeutic for allergic rhinitis and nasal polyposis. Mometasone furoate is also used as an adjunct to anti-bacterials for treating acute rhinosinusitis. In addition, it relieves the symptoms of asthma in both adults and adolescents by exhibiting a broad spectrum of anti-inflammatory properties.

Mometasone furoate is an anti-inflammatory glucocorticoid.

특징 및 장점

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.