M7898
Monoclonal Anti-Thy 1.1 antibody produced in mouse
clone TN-26, purified immunoglobulin, buffered aqueous solution
동의어(들):
Anti-CD90, Anti-CDw90
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About This Item
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추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
TN-26, monoclonal
양식
buffered aqueous solution
종 반응성
mouse
기술
complement-mediated cytotoxicity assay: suitable
indirect immunofluorescence: suitable
동형
IgM
1 of 4
이 품목 | SAB4200497 | WH0007070M1 | SAB4700706 |
|---|---|---|---|
| antibody form purified immunoglobulin | antibody form purified from hybridoma cell culture | antibody form purified immunoglobulin | antibody form purified immunoglobulin |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate FITC conjugate |
| clone TN-26, monoclonal | clone TH350, monoclonal | clone 3F9, monoclonal | clone 5E10, monoclonal |
| Gene Information mouse ... Thy1(21838) | Gene Information human ... THY1(7070) | Gene Information human ... THY1(7070) | Gene Information human ... THY1(7070) |
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| species reactivity mouse | species reactivity mouse, human, rat | species reactivity human | species reactivity pig, nonhuman primates, human, dog |
일반 설명
Monoclonal Anti-Thy 1.1 (mouse IgM isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
Thymus cell antigen 1 (Thy 1.1) is a glycosylphosphatidyl-anchored protein. It belongs to the of the immunoglobulin superfamily. Thy 1.1 is expressed in stem cells, T-cells and neurons.
특이성
Recognizes Thy 1.1 bearing cells and is less than 5% cross-reactive with Thy 1.2 bearing cells. Titer is 1:20,000 as determined by in vitro cytotoxicity against AKR/J thymocytes.
면역원
thymocytes from AKR/J (Thy 1.1) mice.
애플리케이션
Monoclonal Anti-Thy 1.1 antibody produced in mouse has been used in immunopanning and immunofluorescence.
생화학적/생리학적 작용
Studies have shown that mice lacking the protein thymus cell antigen 1 (Thy 1.1) have an increased number of fibroblasts. It suppresses proliferation and enhances apoptosis in dermal fibroblasts, thereby modulating cell growth. This is carried out by regulating the action of β3 integrin.
물리적 형태
Solution in 0.1 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Zhenghui Cheng et al.
BMC molecular and cell biology, 22(1), 21-21 (2021-04-09)
Schwann cells (SCs) play a crucial role in the repair of peripheral nerves. This is due to their ability to proliferate, migrate, and provide trophic support to axon regrowth. During peripheral nerve injury, SCs de-differentiate and reprogram to gain the
J A Cohen et al.
Journal of neuroscience research, 31(4), 622-634 (1992-04-01)
The neu gene, which encodes a putative tyrosine kinase growth factor receptor termed p185neu, was originally identified as a dominant transforming gene in neurogliomas and schwannomas induced by transplacental treatment of rat embryos with ethylnitrosourea. The present studies were undertaken
Wendy A Neveu et al.
American journal of physiology. Cell physiology, 309(9), C616-C626 (2015-09-04)
Idiopathic pulmonary fibrosis is a progressive lung disease that increases in incidence with age. We identified a profibrotic lung phenotype in aging mice characterized by an increase in the number of fibroblasts lacking the expression of thymocyte differentiation antigen 1
Yuqing Feng et al.
Molecular medicine (Cambridge, Mass.), 29(1), 9-9 (2023-01-19)
Retinal ganglion cells (RGCs) apoptosis is a vital manifestation of retinal ischemia/reperfusion (I/R) injury, yet the underlying mechanisms are not well understood. The contribution of long noncoding RNAs (lncRNAs) to this cellular process is currently being explored. Based on a
Glial-mediated neuroprotection: Evidence for the protective role of the NO-cGMP pathway via neuron-glial communication in the peripheral nervous system.
Thippeswamy T, et al.
Glia, 49(2), 197-210 (2005)
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