N193

1-Naphthylacetyl spermine trihydrochloride

• 동의어(들): NASPM trihydrochloride
• 실험식(Hill 표기법): C₂₂H₃₄N₄O · 3HCl
• CAS Number: 1049731-36-3
• Molecular Weight: 479.91
• MDL number: MFCD01321052
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24897539
• NACRES: NA.77

속성

• 분석: ≥95% (HPLC)
• Quality Level: 100
• 양식: powder
• 저장 조건: desiccated; protect from light
• 색상: white
• solubility: H₂O: ≥20 mg/mL
• SMILES string: Cl.Cl.Cl.NCCCNCCCCNCCCNC(=O)Cc1cccc2ccccc12
• InChI: 1S/C22H34N4O.3ClH/c23-12-6-15-24-13-3-4-14-25-16-7-17-26-22(27)18-20-10-5-9-19-8-1-2-11-21(19)20;;;/h1-2,5,8-11,24-25H,3-4,6-7,12-18,23H2,(H,26,27);3*1H
• InChI key: JNEOJAUJWOPWJS-UHFFFAOYSA-N

설명

애플리케이션

1-Naphthylacetyl spermine trihydrochloride has been used for the inhibition of calcium-permeable AMPAR (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor). It has also been used to study the involvement of AMPAR in biphasic activation of stress-activated protein kinase/extracellular signal-regulated kinase-1.

생화학적/생리학적 작용

Blocks Ca²⁺ permeable AMPA receptor channels.

기타 정보

Synthetic analog of Joro spider toxin.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)