O7753

Oxaloacetic acid

powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97% (HPLC)

• 동의어(들): 2-Oxosuccinic acid, Ketosuccinic acid, Oxalacetic acid, Oxobutanedioic acid
• Linear Formula: HOOCCH₂COCOOH
• CAS Number: 328-42-7
• Molecular Weight: 132.07
• Beilstein: 1705475
• EC Number: 206-329-8
• MDL number: MFCD00002592
• UNSPSC 코드: 12352204
• PubChem Substance ID: 24898047
• NACRES: NA.75

속성

• 생물학적 소스: synthetic (organic)
• 제품 라인: BioReagent
• 분석: ≥97% (HPLC)
• 양식: powder
• 기술: cell culture | insect: suitable; cell culture | mammalian: suitable
• solubility: H₂O: 100 mg/mL
• 저장 온도: −20°C
• SMILES string: OC(=O)CC(=O)C(O)=O
• InChI: 1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)
• InChI key: KHPXUQMNIQBQEV-UHFFFAOYSA-N

설명

일반 설명

Oxaloacetic acid is a dicarboxylic acid that is present in every cell in the body. It is a metabolic intermediate of the tricarboxylic acid (TCA) cycle and gluconeogenesis.

애플리케이션

Oxaloacetic acid has been used to evaluate its effect on neuromuscular function and lifespan in amyotrophic lateral sclerosis (ALS) model superoxide dismutase 1 (SOD1) G93A mice. It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) to culture chicken fibroblast (DF-1) cells and chemically immortalized leghorn male hepatoma (LMH) cells for functional validation experiments.

생화학적/생리학적 작용

Oxaloacetic acid plays a vital role in central metabolism. It inhibits succinate dehydrogenase and is a key regulator of mitochondrial metabolism.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges