Name: Pantoprazole sodium hydrate
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₁₆H₁₄F₂N₃O₄S · Na · xH₂O

CAS Number:

718635-09-7

Molecular Weight:

405.35 (anhydrous basis)

UNSPSC 코드:

12352203

PubChem Substance ID:

329819976

NACRES:

NA.77

기술 서비스

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도움 문의

Quality Level

100

분석

≥98% (HPLC)

양식

powder

저장 조건

desiccated

기술

HPLC: suitable
gas chromatography (GC): suitable

색상

white to off-white

solubility

H₂O: ≥20 mg/mL

주관자

Novartis

저장 온도

−20°C

SMILES string

O.[Na+].COc1ccnc(CS(=O)c2nc3cc(OC(F)F)ccc3[n-]2)c1OC

InChI

1S/C16H14F2N3O4S.Na.H2O/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16;;/h3-7,15H,8H2,1-2H3;;1H2/q-1;+1;

InChI key

CGJRLPRCWSHOFU-UHFFFAOYSA-N

유전자 정보

human ... ATP4A(495), ATP4B(496)

애플리케이션

Pantoprazole sodium hydrate has been used:

as a standard in high-performance liquid chromatography (HPLC){58
as a prazole to study its effects on prodrug activation and human immunodeficiency virus 1 (HIV-1) inhibition
to study its effects on breast cancer resistance protein (BCRP) inhibitors in various in vitro membrane preparations from various cell lines

생화학적/생리학적 작용

Pantoprazole has the potential to treat symptoms of heartburn and acid regurgitation. It also has been studied to treat Helicobacter pylori infection and duodenal ulcer.

Pantoprazole is a benzimidazole derivative,activated in acidic environment. It is useful in treating long term prophylaxis and acid-related disorders.

Pantoprazole is a gastric proton pump inhibitor.

특징 및 장점

This compound is featured on the Acid-Sensing (Proton-gated) Ion Channels (ASICs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.