Name: Prazosin hydrochloride
Brand: SIGMA

로그인조직 및 계약 가격 보기

About This Item

실험식(Hill 표기법):

C₁₉H₂₁N₅O₄ · HCl

CAS Number:

19237-84-4

Molecular Weight:

419.86

Beilstein:

4303561

EC Number:

242-903-4

MDL number:

MFCD00058177

UNSPSC 코드:

12352200

PubChem Substance ID:

24277793

NACRES:

NA.77

기술 서비스

도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.

도움 문의

Product Name

Prazosin hydrochloride, ≥99.0% (HPLC)

Quality Level

100

분석

≥99.0% (HPLC)

양식

powder

solubility

H₂O: 0.5 mg/mL
methanol: 6 mg/mL
dilute aqueous acid: insoluble

SMILES string

Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4

InChI

1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H

InChI key

WFXFYZULCQKPIP-UHFFFAOYSA-N

유전자 정보

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Prazosin is a member of the class of α-adrenergic blockers. It is considered as a peripheral vasodilator antihypertensive agent. Prazosin is a derivative of quinazoline.

애플리케이션

Prazosin hydrochloride has been used:

to block the α1adrenergic receptors that mediate sympathetic vasoconstriction in mice
as an α1-adrenoceptor blocker,administered intragastrically in rats
as a vasodilator,administered together with inuslin into the left ventricle of mice for the assessment of its effects on renal functions

생화학적/생리학적 작용

Peripheral α1-adrenoceptor antagonist; vasodilator. Prazosin can be used to treat chronic posttraumatic stress disorder (PTSD). It plays a role in reducing blood pressure by relaxing blood vessels, hence used in the treatment of high blood pressure.

특징 및 장점

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and Melatonin Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.