P8390

Picrotoxinin

• 실험식(Hill 표기법): C₁₅H₁₆O₆
• CAS Number: 17617-45-7
• Molecular Weight: 292.28
• MDL number: MFCD00078765
• UNSPSC 코드: 41116107
• PubChem Substance ID: 24898746
• NACRES: NA.77

속성

• 양식: powder
• Quality Level: 200
• SMILES string: [H][C@@]12OC(=O)[C@]([H])([C@@H]1C(C)=C)[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@@]2([H])[C@]35C
• InChI: 1S/C15H16O6/c1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h6-10,18H,1,4H2,2-3H3/t6-,7+,8+,9-,10-,13-,14-,15+/m1/s1
• InChI key: PIMZUZSSNYHVCU-KBLUICEQSA-N

설명

일반 설명

Picrotoxinin is a component of picrotoxin and can be derived from plants. It is a non-nitrogenous compound.

애플리케이션

Picrotoxinin has been used as an agonist of taste 2 receptor member 14 (TAS2R14) to perform an array-based bitter receptor screening assay and to study the effect of calcium buffering and calcium sensor type on its sensitivity.

생화학적/생리학적 작용

GABA_A receptor antagonist; binds to the GABA receptor-linked Cl⁻ channel.

Picrotoxinin acts as a potent convulsant.

특징 및 장점

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This compound is featured on the Glycine Receptor page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

기타 정보

Active component of picrotoxin

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300
• 예방조치 성명서: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges