생물학적 소스
microbial
Quality Level
분석
~99%
양식
(powderor powder with lumps)
mp
153-155 °C (lit.)
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
저장 온도
2-8°C
SMILES string
N.SC(=S)N1CCCC1
InChI
1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3
InChI key
MDDIUTVUBYEEEM-UHFFFAOYSA-N
유전자 정보
human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846), RELA(5970)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Ammonium pyrrolidinedithiocarbamate is a nuclear factor κB (NF-κB) inhibitor. It functions as a chelating agent, which allows the preconcentration of trace metals from solution. Pyrrolidinedithiocarbamate (PDTC) has antioxidant properties. It inhibits apoptosis in lymphocytes, neurons and vascular endothelial cells.
애플리케이션
Ammonium pyrrolidinedithiocarbamate has been used:
to abrogate the microRNA-146a promoter luciferase reporter activity in human brain cells
- to inhibit nuclear factor κB (NF-κB) mobilization and TNF (tumor necrosis factor) production in human monocytes
- to reduce neutrophil activity in rats
- to prevent Ca2+ influx in adriamycin (ADR)-treated podocytes
to abrogate the microRNA-146a promoter luciferase reporter activity in human brain cells
생화학적/생리학적 작용
Prevents induction of nitric oxide synthetase by inhibiting translation of NOS mRNA; induces apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.