S7448

STF-62247

≥98% (HPLC), solid

• 동의어(들): N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine
• 실험식(Hill 표기법): C₁₅H₁₃N₃S
• CAS Number: 315702-99-9
• Molecular Weight: 267.35
• MDL number: MFCD01121974
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329824583
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• solubility: DMSO: soluble 26 mg/mL; H₂O: insoluble
• 저장 온도: room temp
• SMILES string: Cc1cccc(Nc2nc(cs2)-c3ccncc3)c1
• InChI: 1S/C15H13N3S/c1-11-3-2-4-13(9-11)17-15-18-14(10-19-15)12-5-7-16-8-6-12/h2-10H,1H3,(H,17,18)
• InChI key: KATNUHQNJGNLPW-UHFFFAOYSA-N

설명

애플리케이션

STF-62247 may be used as positive control in autophagy inducing cell signaling studies.

생화학적/생리학적 작용

STF-62247 induces the formation of large vacuoles in the von Hippel-Lindau deficient renal carcinoma cells, a characteristic of autophagy.¹

STF-62247 is a selective inducer of autophagy in VHL-deficient renal cell carcinoma cells.

안전성 정보

• 유해 및 위험 성명서: H413
• 예방조치 성명서: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges