S9318

Sandoz 58-035

>98% (HPLC), powder, acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor

• 동의어(들): 3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenethyl]propanamide, SA 58-035
• 실험식(Hill 표기법): C₃₀H₄₇NOSi
• CAS Number: 78934-83-5
• Molecular Weight: 465.79
• MDL number: MFCD00161339
• UNSPSC 코드: 41121801
• PubChem Substance ID: 24278227
• NACRES: NA.77

속성

• Product Name: Sandoz 58-035, >98% (HPLC), powder
• Quality Level: 100
• 분석: >98% (HPLC)
• 양식: powder
• 색상: white
• solubility: DMSO: 16 mg/mL; H₂O: insoluble
• 주관자: Novartis
• 저장 온도: 2-8°C
• SMILES string: CCCCCCCCCC[Si](C)(C)CCC(=O)NC(Cc1ccc(C)cc1)c2ccccc2
• InChI: 1S/C30H47NOSi/c1-5-6-7-8-9-10-11-15-23-33(3,4)24-22-30(32)31-29(28-16-13-12-14-17-28)25-27-20-18-26(2)19-21-27/h12-14,16-21,29H,5-11,15,22-25H2,1-4H3,(H,31,32)
• InChI key: NBYATBIMYLFITE-UHFFFAOYSA-N
• 유전자 정보: human ... SOAT1(6646) ; rat ... Soat1(81782)

설명

애플리케이션

Sandoz 58-035 was used to induce simultaneous activation of unfolded protein response (UPR) and pattern recognition receptors (PRRs) in mouse peritoneal macrophages.³

생화학적/생리학적 작용

Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor.

Sandoz 58-035 inhibits the accumulation of cholesteryl esters and inhibits the esterification of cholesterol by 95% in arterial smooth muscle cells in culture.¹ It does not affect the triglyceride metabolism by the gut.²

특징 및 장점

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)