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SAB2702133

Sigma-Aldrich

Monoclonal Anti-CEP164 antibody produced in mouse

동의어(들):

Cep164 Antibody, Cep164 Antibody - Monoclonal Anti-CEP164 antibody produced in mouse, NPHP15

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크기 선택

100 μL
$542.00

$542.00


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크기 선택

보기 변경
100 μL
$542.00

About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

$542.00


구입 가능 여부는 고객센터에 문의하십시오.

기술 서비스
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도움 문의

생물학적 소스

mouse

Quality Level

결합

unconjugated

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

13
monoclonal

양식

liquid

종 반응성

human

농도

1 mg/mL

기술

immunocytochemistry: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable
western blot: 1:500-1:3000

유사한 품목 비교

전체 비교 보기

차이점 표시

1 of 4

이 품목
HPA061504SAB4200501I2018
biological source

mouse

biological source

rabbit

biological source

mouse

biological source

mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Gene Information

human ... CEP164(22897)

Gene Information

human ... CEP164(22897)

Gene Information

human ... SFPQ(6421)
mouse ... Sfpq(71514)
rat ... Sfpq(252855)

Gene Information

human ... INS(3630)

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

purified from hybridoma cell culture

antibody form

ascites fluid

clone

13, monoclonal

clone

polyclonal

clone

FC23, monoclonal

clone

K36AC10, monoclonal

species reactivity

human

species reactivity

human

species reactivity

rat, human, mouse

species reactivity

feline, human, rat, horse, rabbit, guinea pig, bovine, monkey, sheep, canine, pig

일반 설명

The centrosomal protein 164 (CEP164) is expressed at the distal ends of the mother centriole. This protein consists of an N-terminal WW domain and three coiled-coil regions. The CEP164 gene is located on the human chromosome at 11q23.3.

면역원

Human Cep164

애플리케이션

Monoclonal Anti-CEP164 antibody produced in mouse has been used in immunoblotting (5 μg/ml).[1]

생화학적/생리학적 작용

The centrosomal protein 164 (CEP164) plays an important role in the synthesis of the primary cilium. This protein interacts with several proteins during ciliogenesis such as Rabin-8, Tau tubulin kinase‐2 (TTBK2), coiled-coil domain containing 41 (CCDC41), and dishevelled (DVL). CEP164 protein is also involved in G2/M checkpoint and nuclear divisions. This protein is a key player in the DNA damage-activated ataxia telangiectasia mutated (ATM)/Rad3-related (ATR) signaling cascade since it is required for the proper phosphorylation of the histone family member X (H2AX), replication protein A (RPA), checkpoint kinase 1 and 2 (CHK1/2). Mutations in the CEP164 gene leads to a condition known as nephronophthisis (NPHP)‐related ciliopathies.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Phosphate-buffered saline, no preservative added.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Rebecca V Walker et al.
Nature communications, 10(1), 4072-4072 (2019-09-08)
The human PKD2 locus encodes Polycystin-2 (PC2), a TRPP channel that localises to several distinct cellular compartments, including the cilium. PKD2 mutations cause Autosomal Dominant Polycystic Kidney Disease (ADPKD) and affect many cellular pathways. Data underlining the importance of ciliary

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