Our comprehensive shRNA product offering consists of over 150,000 pre-cloned shRNA constructs targeting more than 15,000 human and 15,000 mouse genes. The library is available in: gene family sets: gene collections related to specific functional classes such as kinases and ion channels; gene taget sets, sets of shRNA clones that target your favorite gene; and individual shRNA clones. Our shRNA and lentiviral manufacturing platforms utilize dedicated laboratories featuring state-of-the-art robotics, liquid handling and laboratory information management systems (LIMS) to provide superior quality and service for your RNAi research needs.

MISSION^® TRC shRNA bacterial glycerol stocks offer a renewable resource for shRNA plasmids. These plasmids can then be transfected directly, or packaged into lentiviral particles.

MISSION^® shRNA has been used in the generation of damage-regulated autophagy modulator (DRAM) and p73 knockdown cell lines. It has also been used in lentivirus generation and gene knockdown and to investigate the contribution of PAX8 (paired box 8) in ovarian cancer progression.

To see protocols and application data please visit sigma.com/shrna.

Use of this product is subject to one or more license agreements.

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany