SMB00701

Sesamolin

≥97%, from Sesamum indicum (sesame)

• 동의어(들): 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole
• 실험식(Hill 표기법): C₂₀H₁₈O₇
• CAS Number: 526-07-8
• Molecular Weight: 370.35
• UNSPSC 코드: 12352205
• NACRES: NA.25

속성

• 생물학적 소스: Sesamum indicum (sesame)
• Quality Level: 200
• 분석: ≥97%
• 양식: powder
• solubility: DMSO: 10 mg/mL
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• 저장 온도: −20°C
• SMILES string: [H][C@@]12[C@@H](C(C=C3)=CC4=C3OCO4)OC[C@]1([H])[C@@H](OC5=CC6=C(C=C5)OCO6)OC2
• InChI: 1S/C20H18O7/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)27-12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1
• InChI key: ZZMNWJVJUKMZJY-AFHBHXEDSA-N

설명

일반 설명

Sesamolin is a furofuran lignan extracted from Sesamum indicum L. (sesame) seeds. Its solubility is very less in water. The chemical structure of sesamolin comprises two phenylpropanoids with their propyl side attached to a central carbon. It is reported in many other Sesamum species.

생화학적/생리학적 작용

It also exerts antimicrobial, anti-melanogenesis, and neuroprotective effects.

Sesamolin is reported to have beneficial physiological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. It was also found to inhibit lipid peroxidation in rat liver and kidney. Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt′s lymphoma cells, presenting a potential immunotherapeutic value for cancer treatment. In addition, it was demonstrated that sesamolin inhibits β-secretase, presenting an important role for prevention of dementia by daily consumption.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317
• 예방조치 성명서: P280 - P302 + P352
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable